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Epigenetic mechanisms in the development of type 2 diabetes
Trends in Endocrinology and Metabolism, 11/03/09
Pinney SE et al. – Epigenetic regulation of gene expression is one mechanism by which genetic susceptibility and environmental insults can lead to T2D. Therefore, therapeutic agents targeting epigenetic gene regulation can ultimately be used to treat T2D; however, there is much to be learned about genome–wide epigenetic programming of health and disease before these therapies can be used in patient care.
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