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COUP-TFII is Regulated by High Glucose in Endothelial Cells
Hormone and Metabolic Research, 11/02/09
Brunssen C et al. – Downregulation of COUP–TFII by shRNA leads to downregulation of E–selectin and upregulation of eNOS and glucose transporters. The data suggest that COUP–TFII is regulated by glucose in a time– and dose–dependent manner in endothelial cells. COUP–TFII might affect endothelial function in a diabetic background.
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