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Expression and Function of Endocannabinoid Receptors in the Human Adrenal Cortex
Hormone and Metabolic Research, 11/02/09
Ziegler CG et al. – Anandamide inhibited basal release and stimulated release of adrenocortical steroids (corticosterone and aldosterone); this effect was reversed by CB1 antagonist (SR141716A). Therefore, the endocannabinoid system at the level of the adrenal, can directly influence adrenocortical steroidogenesis.
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