Endocrinology Medical News about checkpoint kinase 2 gene

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Variation in the checkpoint kinase 2 gene is associated with type 2 diabetes in multiple populations
Acta Diabetologia, 10/29/09

North KE et al. – One CHEK2 variant, rs4035540, was associated with an increased risk of type 2 diabetes in HyperGEN participants, two replication samples, and in the meta–analysis. These results may suggest a new pathway in the pathogenesis of type 2 diabetes that involves pancreatic beta–cell damage and apoptosis.

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Very Late-Onset Group B Streptococcus Meningitis, Sepsis, and Systemic Shigellosis due to Interleukin-1 Receptor–Associated Kinase-4 Deficiency
Clinical Infectious Diseases, 10/14/09 Relevance Score: 79%

A Polymorphism within the Fructosamine-3-kinase Gene is Associated with HbA1c Levels and the Onset of Type 2 Diabetes Mellitus
Experimental and Clinical Endocrinology & Diabetes, 11/02/09 Relevance Score: 78%

Activity of the multikinase inhibitor dasatinib against ovarian cancer cells
British Journal of Cancer, 11/02/09 Relevance Score: 78%

Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer
Arthritis Research & Therapy, 10/07/09 Relevance Score: 70%

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Infection and Immunity, 11/16/09 Relevance Score: 69%