Endocrinology Medical News about Pituitary Hormone Deficiency

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A Novel Mutation (V101A) of the LHX4 Gene in a Japanese Patient with Combined Pituitary Hormone Deficiency
Experimental and Clinical Endocrinology & Diabetes, 11/02/09

Tajima T et al. – LHX4, a LIM–homeodomain transcription factor, is required for development of the pituitary and nervous system. The objective of the study was to clarify the molecular basis of a Japanese patient of CPHD with a small anterior pituitary and an ectopic posterior pituitary. The results identify a novel loss of function mutation of the LHX4 gene in a Japanese patient with CPHD.

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Hypopituitarism due to sports related head trauma and the effects of growth hormone replacement in retired amateur boxers
Pituitary, 10/29/09 Relevance Score: 81%

Growth without Growth Hormone and Similar Dysmorphic Features in Three Patients with Sporadic Combined Pituitary Hormone Deficiencies
Hormone Research, 10/27/09 Relevance Score: 81%

A Molecular Basis for Variation in Clinical Severity of Isolated Growth Hormone Deficiency Type II
Journal of Clinical Endocrinology and Metabolism, 10/29/09 Relevance Score: 80%

Comparison of glucose and lipid metabolism and bone mineralization in patients with growth hormone deficiency with and without long-term growth hormone replacement
Metabolism-Clinical and Experimental, 10/26/09 Relevance Score: 80%

Genetic forms of hypopituitarism and their manifestation in the neonatal period
Early Human Development, 10/30/09 Relevance Score: 79%