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Effect of hyperinsulinemia and very-low-calorie diet on interstitial cytokine levels in subcutaneous adipose tissue of obese women
Endocrinology and Metabolism, 11/02/09
Siklova–Vitkova M et al. – Hyperinsulinemia upregulates the interstitial levels of MCP–1, IL–6, and IL–8 in SCAT in obese women, whereas it does not affect IL–1beta, IL–10, TNFalpha, and PAI–1 levels. Hypocaloric diet associated with weight reduction enhances the hyperinsulinemia–induced upregulation of MCP–1, IL–6, and IL–8 in SCAT.
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