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Effects of Endogenous Growth Differentiation Factor 9 on Activin A-Induced Inhibin B Production in Human Granulosa-Lutein Cells
Journal of Clinical Endocrinology and Metabolism, 11/06/09
Shi F–T et al. – The authors report here for the first time autocrine roles for endogenous GDF9 in hGL cells in enhancing activin A–induced betaB–subunit mRNA and inhibin B levels via key components of the activin signaling pathway. However, the relative contributions of GDF9 in granulosa cells vs. oocyte as autocrine/paracrine regulators of betaB–subunit and inhibin B production in normal and abnormal human ovarian functions remain to be determined.
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Today in Basic Science/Genetics...keeping you current
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Today in Fetal Development...keeping you current
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Lactate distribution in culture medium of human myometrial biopsies incubated under different conditions
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