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Postmenopausal Women With Osteopenia Have Higher Cortical Porosity and Thinner Cortices at the Distal Radius and Tibia Than Women With Normal aBMD: An In Vivo HR-pQCT Study
Journal of Bone and Mineral Research, 10/28/09
Nishiyama KK et al. – Increases in cortical porosity (Ct.Po) and decreases in cortical thickness (Ct.Th) are associated with increased bone fragility. The purpose of this study was to validate an auto–segmentation method for high–resolution peripheral quantitative computed tomography (HR–pQCT) scans. The method offers promise as a valuable tool to measure Ct.Po and Ct.Th in vivo and investigate associations between cortical bone structure, age and disease status.
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