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Friedenberg FK et al. – The frequency of ambulatory visits in the United States for gastroesophageal reflux disease increased significantly between 1995 and 2006. The use of PPI therapy is increasing even more substantially. Older age, female gender, and use of calcium channel blockers were associated with a higher frequency of GERD visits. Health–care utilization for this disorder is increasing perhaps due to ever–increasing epidemic of obesity.


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