Endocrinology Medical News about mitochondrial function

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Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function
Diabetes, 11/05/09

Karakelides H et al. – The results demonstrate that age–related reductions in insulin sensitivity are likely due to an age–related increase in adiposity rather than a consequence of advanced chronological age. The results also indicate that age–related decrease in muscle mitochondrial function is neither related to adiposity or insulin sensitivity. Of interest, a higher mitochondrial ATP production capacity was noted in the men, whereas the women were more insulin sensitive.

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Mitochondrial Function and Insulin Resistance in Overweight and Normal-Weight Children
Journal of Clinical Endocrinology and Metabolism, 10/29/09 Relevance Score: 69%

Effect of Short-Term Free Fatty Acids Elevation on Mitochondrial Function in Skeletal Muscle of Healthy Individuals
Journal of Clinical Endocrinology and Metabolism, 11/11/09 Relevance Score: 68%

Substrate-Specific Derangements in Mitochondrial Metabolism and Redox Balance in the Atrium of the Type 2 Diabetic Human Heart
JACC - Journal of the American College of Cardiology, 11/09/09 Relevance Score: 67%

Estrogen-receptor-mediated protection of cerebral endothelial cell viability and mitochondrial function after ischemic insult in vitro
Journal of Cerebral Blood Flow & Metabolism, 11/05/09 Relevance Score: 66%

Prevention of I/R injury in fatty livers by ischemic preconditioning is associated with increased mitochondrial tolerance: the key role of ATPsynthase and mitochondrial permeability transition
Transplant International, 10/22/09 Relevance Score: 66%