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Paris F et al. – Cushing's syndrome (CS) may develop at any time in childhood. In the neonatal period, the major cause is the overactivation of adrenal cells within the context of McCune–Albright syndrome (MAS). The authors report here a case of isolated neonatal CS as the initial evidence of MAS. This female newborn later developed the classical triad of MAS, reinforcing this diagnosis. Cushing's syndrome in infants, even when isolated, may suggest a diagnosis of MAS.

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