Endocrinology Medical News about BclI polymorphism

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BclI polymorphism of the glucocorticoid receptor gene is associated with decreased bone mineral density in patients with endogenous hypercortisolism
Clinical Endocrinology, 10/15/09

Szappanos A et al. – The BclI, N363S, ER22/23EK and A3669G polymorphisms of the GR gene probably do not modify the risk for the development of CD or ACS. Contrary to healthy subjects, however, the BclI polymorphism may modify the skeletal sensitivity to glucocorticoids in patients with endogenous glucocorticoid excess.

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TNF superfamily gene polymorphism as prognostic factor in early breast cancer
Journal of Cancer Research & Clinical Oncology, 11/10/09 Relevance Score: 46%

Interleukin-12 gene polymorphism and cervical cancer risk
American Journal of Clinical Oncology, 10/06/09 Relevance Score: 45%

Association of IL-1B genetic polymorphisms with an increased risk of opioid and alcohol dependence
Pharmacogenetics and genomics, 10/30/09 Relevance Score: 44%

EGF61A > G polymorphism as predictive marker of clinical outcome to first-line capecitabine and oxaliplatin in metastatic colorectal cancer
Annals of Oncology, 10/28/09 Relevance Score: 44%

The -283C/T polymorphism of the DNMT3B gene influences the progression of joint destruction in rheumatoid arthritis
Rheumatology International, 10/01/09 Relevance Score: 44%