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See Latest ArticlesHomozygosity of the Polymorphism MICA5.1 Identifies Extreme Risk of Progression to Overt Adrenal Insufficiency among 21-Hydroxylase Antibody-Positive Patients with Type 1 Diabetes
Journal of Clinical Endocrinology and Metabolism, 10/15/09
Triolo TM et al. – Identifying extreme risk should facilitate monitoring of progression from 21OH antibody positivity to overt AD. The HLA–DR3/0404 genotype defines high–risk subjects for adrenal autoimmunity. MICA5.1/5.1 may define those at highest risk for progression to overt AD, a feature unique to AD and distinct from T1D.
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