Endocrinology Medical News about Diabetic Neuropathies Cannabis Sativex

Become a Member Today!
Register

Most Viewed Abstracts

1. Report Shows Shift in Starting Salaries for Physicians

2. AHA Guidelines on Cardiac CT for Assessing Coronary Artery Disease

3. Rapid correction of low vitamin D status in nursing home residents

4. 2008 Exclusive Survey—Earnings: Good news for primary care income

5. Medicare pay-for-reporting effort draws fire from frustrated doctors

Your Article Summary

See Latest Articles

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

A Randomised Placebo Controlled Double Blind Clinical Trial of Cannabis Based Medicinal Product (Sativex) in Painful Diabetic Neuropathy: Depression is a Major Confounding Factor
Diabetes Care, 10/09/09

Selvarajah D et al. – This first ever, trial assessing the efficacy of cannabis has shown it to be no more efficacious than placebo in painful–DPN. Depression was a major confounder and may have important implications for future painful–DPN trials.

Methods

In this randomized controlled trial, 30 subjects with painful–DPN received daily Sativex or placebo.
Primary outcome measure was change in mean daily pain scores and secondary outcome measures included quality of life assessments.

Results

There was significant improvement in pain scores in both groups but mean change between groups was not significant.
There were no significant differences in secondary outcome measures.
Patients with depression had significantly greater baseline pain scores that improved regardless of intervention.

<< Previous
Influence of Etiology of Heart Failure on the Obesity Paradox

Next >>
Fracture risk assessment in postmenopausal women

Characteristics of patients with chronic pain accessing treatment with medical cannabis in Washington State
Journal of Opioid Management, 11/03/09 Relevance Score: 79%

Transforming growth factor beta 1 as a biomarker of diabetic peripheral neuropathy: cross-sectional study
Journal of Diabetes and its Complications, 10/12/09 Relevance Score: 69%

Tactile direction discrimination and vibration detection in diabetic neuropathy
Acta Neurologica Scandinavica, 10/07/09 Relevance Score: 69%

New diagnostic tests for diabetic distal symmetric polyneuropathy
Journal of Diabetes and its Complications, 11/13/09 Relevance Score: 68%

Prevalence and Risk Factors of Somatic and Autonomic Neuropathy in Prediabetic and Diabetic Patients
Neuroepidemiology, 11/11/09 Relevance Score: 68%