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Genome-wide mechanisms of nuclear receptor action
Trends in Endocrinology and Metabolism, 10/19/09
Biddie SC et al. – The authors highlight emerging roles for the epigenome, chromatin remodeling, histone modification, histone variants and long–range chromosomal interactions in nuclear receptor binding and receptor–dependent gene regulation. These mechanisms contribute importantly to the action of nuclear receptors in health and disease.
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