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See Latest ArticlesRole of the Kidney in the Prenatal and Early Postnatal Programming of Hypertension
American Journal of Physiology: Renal Physiology, 10/01/09
Baum M – The causes for the increase in blood pressure by perinatal insults are likely multifactorial and involve a reduction in nephron number, dysregulation of the systemic and intrarenal renin–angiotensin system, increased renal sympathetic nerve activity and increased tubular sodium transport. Understanding the mechanism for the increase in blood pressure and renal injury resulting from prenatal insults may lead to therapies that prevent hypertension and the development of chronic kidney and cardiovascular disease.
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