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Long-term glycaemic control with metformin–sulphonylurea–pioglitazone triple therapy in PROactive (PROactive 17)
Diabetic Medicine, 10/02/09

Scheen AJ et al. – Intensifying an existing dual oral therapy regimen to a triple oral regimen by adding pioglitazone to the classical metformin–sulphonylurea combination resulted in sustained improvements in glycaemic control and reduced progression to insulin therapy. The advantages and disadvantages of adding pioglitazone instead of adding basal insulin should be assessed further.

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