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See Latest ArticlesIncreased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance
Endocrinology and Metabolism, 09/25/09
Liu H–Y et al. – Increased basal Akt–dependent insulin signaling suppresses mitochondrial production, increases ectopic fat accumulation, induces oxidative stress, and desensitizes insulin signaling in subjects with insulin resistance and hyperinsulinemia.
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