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Association of Polymorphisms in Genes of the Homologous Recombination DNA Repair Pathway and Thyroid Cancer Risk
Thyroid, 09/25/09
Bastos HN et al. – Since XRCC3 is involved in the assembly and stabilization of RAD51 protein multimers at double–strand break sites, we cannot exclude that the interaction of both polymorphisms can lead to a decreased DNA repair capacity and consequently increased risk for thyroid cancer.
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