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See Latest ArticlesSubchondral bone marrow lesions are highly associated with, and predict subchondral bone attrition longitudinally: the MOST study
Osteoarthritis and Cartilage , 09/18/09
Roemer FW et al. – Prevalent and incident SBA is strongly associated with subchondral BMLs in the same subregion
Methods- Subjects with available baseline and 30-months follow-up MRI were included
- Subchondral BMLs and SBA were scored semiquantitatively from 0 to 3 in 10 tibiofemoral subregions
- 1025 knees were included
- 8.9% of the analyzed knee subregions showed SBA present at baseline and 9.2% of subregions exhibited prevalent subchondral BMLs
- The adjusted OR for prevalent SBA for subregions with prevalent BMLs was 18.8
- A larger BML size was directly associated with an increased risk of prevalent SBA
- 195 (2.2%) subregions exhibited incident SBA at follow-up
- The adjusted OR for incident SBA was 5.3 when compared to subregions without BMLs as the reference
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