Endocrinology Medical News about vertebral fractures

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Low serum level of the endogenous secretory receptor for advanced glycation end-products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes
Diabetes Care, 09/28/09

Yamamoto M et al. – Patients with type 2 diabetes mellitus (T2DM) are known to have an increased risk for fracture compared to non–T2DM controls, despite their higher bone mineral density (BMD). The results show that serum esRAGE level and esRAGE/pentosidine ratio are more useful than BMD for assessing the risk of VFs in T2DM patients.

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