Endocrinology Medical News about intervertebral disc; estrogens

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Estrogens and the intervertebral disc
Menopause International, 09/04/09

Calleja–Agius J et al. – It has been shown that menopause has a negative effect on bone and on intervertebral discs. Estrogen has a beneficial effect of preserving the health of collagen–containing tissues, including the intervertebral disc. The function of the spine is impaired if there is a loss of disc tissue. Narrowing of the disc space due to degeneration of intervertebral discs is associated with a significantly increased risk of vertebral fractures. Estrogen should be seen as the first–choice therapy for bones and other collagen–rich tissues, such as intervertebral discs, because it maintains homeostasis of the bone–remodelling unit.

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