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See Latest ArticlesThe midregional portion of proadrenomedullin is an independent predictor of left ventricular mass index in hypertension
Metabolism-Clinical and Experimental, 08/31/09
Bhandari SS et al. – Left ventricular hypertrophy (LVH) is a risk factor for cardiovascular disease. Elevated natriuretic peptides in LVH have spurred interest that biomarkers may play a role in screening programs. Adrenomedullin (ADM) is a 52–amino acid peptide mediating vasorelaxation, natriuresis, and diuresis. The high negative predictive value of the MRproADM assay allows it to be used as a rule–out test for LVH when stratifying patients into high or low risk. Patients who test positive would necessitate echocardiography, enabling better resource allocation.
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