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See Latest ArticlesHigh-resolution genomic profiling reveals gain of chromosome 14 as a predictor of poor outcome in ileal carcinoids
Endocrine-Related Cancer, 08/28/09
Nilsson O et al. – The majority of tumours showed loss of chromosome 18, which most likely represents a primary event in the development and pathogenesis of tumours. A different genetic pathway is operative in a subgroup of tumours; this is characterized by gain of chromosome 14 and is strongly associated with poor prognosis. Predictive fluorescence in situ hybridization analysis of chromosome 14 status in patients with ileal carcinoids is suggested.
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