Endocrinology Medical News about GHRP-6 and GHRH

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Partial restoration of GH responsiveness to ghrelin in Cushing's disease after 6 months of ketoconazole treatment: comparison with GHRP-6 and GHRH
European Journal of Endocrinology, 08/25/09

Correa–Silva S et al. – Ghrelin–induced GH release increases significantly after 6 months of ketoconazole treatment in CD. This could suggest that a decrease in cortisol levels during this time period can partially restore glucocorticoid–induced GH suppression in CD. GH–releasing mechanisms stimulated by ghrelin/GHS could be more sensitive, as no changes in GHRH–induced GH release were observed.

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Acromegaly with negative pituitary MRI and no evidence of ectopic source: the role of transphenoidal pituitary exploration
Pituitary, 11/18/09 Relevance Score: 40%

A Reappraisal of Diagnosing GH Deficiency in Adults: Role of Gender, Age, Waist Circumference, and Body Mass Index
Journal of Clinical Endocrinology and Metabolism, 10/12/09 Relevance Score: 40%