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Survey of vitamin D levels among post-menopausal Filipino women with osteoporosis
International Journal of Rheumatic Diseases, 08/20/09
Raso AAP et al. – Among the group of women with post-menopausal osteoporosis included in this study, only 36% had insufficient levels of 25-hydroxyvitamin D, with none of the subjects having deficient 25-hydroxyvitamin D levels. 64% had normal serum 25-hydroxyvitamin D levels – comparatively higher than that reported in the literature, suggesting the possible contribution of factors other than vitamin D deficiency in post-menopausal Filipino women with osteoporosis.
Methods- Study aims to determine the prevalence of vit D inadequacy in a group of Filipino post-menopausal women with osteoporosis
- 70 otherwise healthy post-menopausal Filipino women; diagnosed with osteoporosis by central DEXA technique
- Levels of serum 25-hydroxyvitamin D were measured using ELISA
- Mean age: 70±8 yrs, with an average of 22±10 yrs since menopause; mean BMI of 22±1 kg/m2
- Only 30% were on calcium plus vit D supplementation
- Overall serum 25-hydroxyvitamin D levels ranged from 48-128 nmol/L, with a mean of 87±20.48 nmol/L
- Serum 25-hydroxyvitamin D levels were divided as follows:
- 80-140 nmol/L (adequate)
- 25-79 nmol/L (inadequate/insufficient), and
- < 25 nmol/L (deficient)
- 64% of subjects had adequate levels while 36% had inadequate levels of 25-hydroxyvitamin D
- No subjects with deficient levels of 25-hydroxyvitamin D
- Fischer's exact test did not show an association between BMD and 25-hydroxyvitamin D
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