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From isolated growth hormone deficiency to multiple pituitary hormone deficiency: an evolving continuum
European Journal of Endocrinology, 08/17/09
Klose M et al. – Both AO–iGHD and –MPHD patients have similar baseline clinical presentation and respond equally well to 2 yrs of GH replacement. Hypopituitarism in adults seems to be a dynamic condition where new deficiencies can appear years from the initial diagnosis, and careful endocrine follow–up of all hypopituitary patients, including those with iGHD, is warranted.
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