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Validity and Reproducibility of Measurement of Islet Autoreactivity by T-cell Assays in Subjects with Early Type 1 diabetes
Diabetes, 08/14/09
Herold KC et al. – The CI, UK–ELISPOT, and TCP assays can distinguish responses from patients with Type 1 diabetes and healthy control subjects. The limited reproducibility of the measurements overall and of responses to individual analytes may reflect the difficulty in detection of low frequency of antigen specific T cells or variability in their appearance in peripheral blood.
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