Endocrinology Medical News about Intrauterine Growth Retardation

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Changes in GH/IGF-1 Axis in Intrauterine Growth Retardation: Consequences of Fetal Programming
Hormone and Metabolic Research, 07/22/09

Setia S et al. – Fetal growth is a complex process that depends on the genotype and epigenotype of the fetus, maternal nutrition, the availability of nutrients and oxygen to the fetus, intrauterine insults, and a variety of growth factors and proteins of maternal and fetal/placental origin. In the fetus, growth hormone (GH) plays little or no role in regulating fetal growth, and insulin–like growth factors (IGFs) control growth directly independent of fetal GH secretion.

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