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See Latest ArticlesImpact of the exon 3-deleted GH receptor polymorphism on baseline height and the growth response to recombinant human growth hormone therapy in growth hormone deficient (GHD) and non-GHD children with short stature: a systematic review and meta-analysis
Journal of Clinical Endocrinology and Metabolism, 07/08/09
Wassenaar MJE et al. - The meta-analysis in prepubertal children with short stature indicates that GHRd3 is associated with increased baseline height in GHD, but not in non-GHD. Furthermore, GHRd3 stimulates growth velocity by an additional effect of 0.5 cm during the first year of rhGH treatment and this effect is more pronounced at lower doses of rhGH and higher age.
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