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Fernandez-Veledo S et al. - TNF-alpha induces insulin resistance on glucose uptake in human visceral but not in subcutaneous adipocytes, suggesting depot-specific effects of TNF-alpha on glucose uptake. Activation of JNK1/2 appears to be involved in serine phosphorylation of IRS1 and subsequently insulin resistance on glucose uptake, a state that can be reversed by LXR agonists.


Today in Basic Science/Genetics...keeping you current

Body Composition and Bone Mineral Density in Children with Premature Adrenarche and the Association of LRP5 Gene Polymorphisms with Bone Mineral Density
Journal of Clinical Endocrinology and Metabolism, 10/14/09

Ethanol extract of Fructus Ligustri Lucidi promotes osteogenesis of mesenchymal stem cells
Phytotherapy Research, 10/13/09

Clock genes, intestinal transport and plasma lipid homeostasis
Trends in Endocrinology and Metabolism, 10/16/09

Today in Diabetes...keeping you current

Amitriptyline vs. pregabalin in painful diabetic neuropathy: a randomized double blind clinical trial
Diabetic Medicine, 10/01/09

Hemoglobin A1C and diabetes diagnosis: The Rancho Bernardo Study
Diabetes Care, 10/28/09

Tests for Screening and Diagnosis of Type 2 Diabetes
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Today in Obesity...keeping you current

Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study
The Lancet - Early Online Publication, 10/23/09

Increased food energy supply is more than sufficient to explain the US epidemic of obesity
American Journal of Clinical Nutrition, 10/15/09

Psychiatrists' Perceptions and Practices in Treating Patients' Obesity
Academic Psychiatry, 10/16/09

Today in Pharmacology/kinetics...keeping you current

Amitriptyline vs. pregabalin in painful diabetic neuropathy: a randomized double blind clinical trial
Diabetic Medicine, 10/01/09

Safety and efficacy of testosterone gel in the treatment of male hypogonadism
Clinical Interventions in Aging, 10/12/09

Bisphosphonate therapy: When not to monitor BMD
The Journal of Family Practice, 11/02/09


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