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Genetic overlap between polycystic ovary syndrome and bipolar disorder: The endophenotype hypothesis
Medical Hypotheses, 06/26/09
Jiang B et al. - Polycystic Ovary Syndrome (PCOS) is a polygenic disorder caused by the interaction of susceptible genomic polymorphisms with environmental factors. PCOS, characterized by hyperandrogenism and menstrual abnormalities, has a higher prevalence in women with Bipolar Disorder (BD). Endophenotypes such as insulin resistance, obesity, and hyperglycemia are common among BD and PCOS patients, suggesting some degree of pathophysiological overlap.
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Comparison of Simvastatin and Metformin in Treatment of Polycystic Ovary Syndrome: Prospective Randomized Trial
Journal of Clinical Endocrinology and Metabolism, 11/20/09
Timetable of effects of testosterone administration to hypogonadal men on variables of sex and mood
The Aging Male, 11/13/09
Safety and efficacy of testosterone gel in the treatment of male hypogonadism
Clinical Interventions in Aging, 10/12/09
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