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Biochemical Factors Governing the Steady-State Estrone/Estradiol Ratios Catalyzed by Human 17beta-Hydroxysteroid Dehydrogenases Types 1 and 2 in HEK-293 Cells
Endocrinology, 06/29/09
Auchus RJ et al. - The findings suggest that additional structural features, beyond the lack of a specific arginine residue, disfavor NADPH binding thus and support E2 oxidation by 17betaHSD2 in intact cells.
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