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See Latest ArticlesInhibition of NFkB or Bax prevents Endoplasmic Reticulum Stress- but not Nitric Oxide-mediated Apoptosis in INS-1E cells
Endocrinology, 06/29/09
Mandrup-Poulsen T et al. - The data suggest that NO generation and direct SERCA2 inhibition cause two quantitative and qualitative different forms of ER stress. In contrast to NO, direct ER stress induced by SERCA-inhibition causes activation of ER stress signalling pathways and elicit proapoptotic signalling via NFkB and Bax.
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Today in Basic Science/Genetics...keeping you current
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Dual promoter regulation of death-associated protein kinase gene leads to differentially silenced transcripts by methylation in cancer
Carcinogenesis, 12/15/09
HIF-1 is induced via EGFR activation and mediates resistance to anoikis-like cell death under lipid rafts/caveolae-disrupting stress
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Gene expression of PPARgamma and PGC-1alpha in human omental and subcutaneousadipose tissue is related to insulin resistance markers and mediates beneficial effects of physical training
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