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Stuart CA et al. - Insulin causes GLUT12 to translocate from an intracellular location to the plasma membrane in normal human skeletal muscle. Translocation of GLUT12 in cultured myoblasts was dependent of activation of PI3-K. GLUT12 may have evolutionarily preceded GLUT4 and now provides redundancy to the dominant GLUT4 system in muscle.

Today in Basic Science/Genetics...keeping you current

Ex vivo TCR-induced leukocyte gene expression of inflammatory mediators is increased in type 1 diabetic patients but not in overweight children
Diabetes/Metabolism Research and Reviews, 12/08/09

Altered resting state attentional networks in diabetic neuropathic pain
Journal of Neurology, Neurosurgery, and Psychiatry , 12/07/09

Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease
Lipids in Health and Disease, 12/04/09