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Effect of a local heating device on insulin and glucose pharmacokinetic profiles in an open-label, randomized, two-period, one-way crossover study in patients with type 1 diabetes using continuous subcutaneous insulin infusion
Clinical Therapeutics, 06/19/09

Raz I et al. - In this pilot study, use of the InsuPatch was associated with significant decreases in Tmax and T50%max and increases in insulin AUC and Cmax of subcutaneous infused rapid-acting insulin analogues, resulting in a lower postprandial glucose excursion in these patients with type 1 diabetes mellitus treated with CSII.

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