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Clinical characteristics and associated comorbidities in diabetic patients with restless legs syndrome
Experimental and Clinical Endocrinology & Diabetes, 06/24/09

Greco D et al. – Restless legs syndrome (RLS) is a serious and not uncommon problem for diabetes mellitus pts. This syndrome is closely related to diabetic neuropathy and probably to metabolic factors in its pathogenesis. RLS diagnosis is often delayed; however, because RLS can be effectively treated, better education of the general medical community is necessary for greater awareness of RLS.

Methods

Study of clinical characteristics and risk factors associated with RLS among diabetes pts
Retrospective study of all diabetic inpatients with RLS over 18 mo
Detailed history, blood laboratory profile and electrophysiological evaluation for all pts

Results

RLS in 23 pts
RLS pts had poorly controlled diabetes and had associated comorbidities
Comorbidities: high prevalence of diabetic neuropathy (96%) and metabolic syndrome (74%)
Median duration of RLS symptoms onset: 2.8 yrs

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