Diabetes News

Endocrinology

sponsor

Your Article Summary

(Click the title below to leave the MDLinx Network and go to the Journal's Website)

Smith BR et al. - Although it has been postulated that stimulating and blocking TRAbs bind to different regions on the TSHR, the authors studies showed that antibodies of both types bind well to the TSHR containing only N-terminal amino acids 22-260. Whether TRAbs make contact with other parts of the TSHR in order to produce their biological effects (stimulation or blocking) remains to be elucidated.

Related Articles

Human TSH receptor ligands as pharmacological probes with potential clinical application
Expert Review of Endocrinology & Metabolism, 11/17/09    Relevance Score: 68%

Thyroid Eye Disease: A Historical Perspective
Orbit - The International Journal on Orbital Disorders, Oculoplastic and Lacrimal Surgery, 11/12/09    Relevance Score: 65%

Can Autoimmunity Against Calsequestrin Explain the Eye and Eyelid Muscle Inflammation of Thyroid Eye Disease?
Orbit - The International Journal on Orbital Disorders, Oculoplastic and Lacrimal Surgery, 11/12/09    Relevance Score: 64%

The Effects of Opioids and Opioid Analogs on Animal and Human Endocrine Systems
Endocrine Reviews, 11/11/09    Relevance Score: 63%

Targeting the NMDA Receptor Subunit NR2B for the Treatment of Neuropathic Pain
Neurotherapeutics, 10/05/09    Relevance Score: 47%