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Hyperparathyroidism during pregnancy and the effect of rising calcium on pregnancy loss: a call for earlier intervention
Clinical Endocrinology, 06/19/09
Norman J et al. - HPT during pregnancy is under recognized and is associated with a 3·5-fold increase in miscarriage rates. Pregnancy loss often occurs in the second trimester and is associated with multiple miscarriages when not addressed. Pregnancy loss is more common as calcium levels exceed 11·4 mg/dl (2·85 mmol/l), but can be seen at all elevated calcium levels. Emphasis is placed on earlier recognition and surgical cure before becoming pregnant, however, once pregnant, surgery should be offered early in the second trimester for those with calcium levels above 11·4 mg/dl.
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