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See Latest ArticlesMonitoring disease activity using GH and IGF-I in the follow-up of 501 patients with acromegaly
Clinical Endocrinology, 06/17/09
Sherlock M et al. - There is a close relationship between a basal fasting GH < 2·5 mug/l and nadir/mean GH < 2·5 mug/l during OGTT/GHDC. There is a large discordance between disease activity when assessed by GH and IGF-I which is further increased by radiotherapy. These observations illustrate the challenge of defining appropriate biochemical end-points to achieve control of disease and normalization of mortality in acromegaly.
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