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See Latest ArticlesAspirin and clopidogrel: efficacy and resistance in diabetes mellitus
Best Practice & Research Clinical Endocrinology & Metabolism, 06/15/09
Angiolillo DJ et al. - Aspirin and clopidogrel, used either solely or in combination, are associated with improved clinical outcomes in high-risk patients, diabetics patients treated with antiplatelet agents remain at higher risk of recurrent ischemic events. In this chapter the efficacy of currently available oral antiplatelet agents in preventing ischemic events is reviewed. In addition, the antiplatelet ‘resistance’ phenomenon in the diabetic population and its impact on clinical outcomes is summarized. Finally, future developments in the field directed towards individualized treatment strategies and novel antiplatelet agents are examined.
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