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MacPherson L et al. - The data show that the AF2 domain contributes to dioxin-induced recruitment of ER-alpha to AHR target genes, but that both the AF1 and AF2 domains are required for ER-alpha -dependent increases in AHR activity.

Today in Basic Science/Genetics...keeping you current

Ex vivo TCR-induced leukocyte gene expression of inflammatory mediators is increased in type 1 diabetic patients but not in overweight children
Diabetes/Metabolism Research and Reviews, 12/08/09

Altered resting state attentional networks in diabetic neuropathic pain
Journal of Neurology, Neurosurgery, and Psychiatry , 12/07/09

Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease
Lipids in Health and Disease, 12/04/09