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ACTH-independent macronodular adrenal hyperplasia
Best Practice & Research Clinical Endocrinology & Metabolism, 06/19/09
Lacroix A et al. - AIMAH presents as incidental radiological finding or with subclinical or overt CS, occasionally with secretion of mineralocorticoids or sex steroids. In several familial cases of AIMAH, specific aberrant hormone receptors are functional in the adrenal of affected members. Additional somatic genetic events related to cell cycle regulation, adhesion and transcription factors occur in addition in the various nodules over time. The identification of aberrant receptors can offer a specific pharmacological approach to prevent progression and control abnormal steroidogenesis; alternatively, unilateral or bilateral adrenalectomy becomes the treatment of choice.
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Clinical Predictors and Algorithm for the Genetic Diagnosis of Pheochromocytoma Patients
Clinical Cancer Research, 10/19/09
The pituitary-adrenal axis in adult thalassaemic patients
European Journal of Endocrinology, 11/02/09
A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials of DHEA Treatment Effects on Quality of Life in Women with Adrenal Insufficiency
Journal of Clinical Endocrinology and Metabolism, 10/09/09
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