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Effects of metformin versus ethinyl-estradiol plus cyproterone acetate on ambulatory blood pressure monitoring and carotid intima media thickness in women with the polycystic ovary syndrome
Fertility and Sterility, 06/03/09
Escobar-Morreale HF et al. - Metformin treatment decreased daytime ABPM recordings whereas Diane35 Diario exerted the opposite effect. The safer blood pressure profile of metformin should be considered in PCOS patients who present with a history of hypertension or who are at risk for this disorder. Treatment with either Diane35 Diario or metformin improved CIMT mean values.
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