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See Latest ArticlesProblems and Controversies in the Histopathology of Thyroid Carcinomas of Follicular Cell Origin
Archives of Pathology and Laboratory Medicine, 05/07/09
Ghossein R - Recent data show that prognosis and therapy for many disease entities can be better delineated if a meticulous microscopic examination is performed. An accurate assessment of the extent of invasion (especially vascular) is crucial. Proliferative grading (ie, mitosis and necrosis) is of high prognostic value and should be looked for in every specimen. In addition, molecular data gathered to date can help reassess these tumors at the histologic level. Classification proposals based on personal experience rather than adequate and careful clinical follow-up should be discouraged.
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