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The relationship between central adrenal insufficiency and sleep-related breathing disorders in children with Prader-Willi syndrome
Journal of Clinical Endocrinology and Metabolism, 05/01/09
Joosten KFM et al. - In children with PWS, the central apnea index increased significantly after metyrapone administration, particularly in those with CAI during stress. In addition, children with CAI had a higher central apnea index compared to those without, several months prior to the metyrapone test.
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