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Secondary Adrenal Insufficiency due to Opiate Therapy - Another Differential Diagnosis Worth Consideration
Experimental and Clinical Endocrinology & Diabetes, 04/22/09
Schimke KE et al. - The authors report on a 64-year-old patient in whom fentanyl therapy was found to be responsible for the induction of secondary adrenal insufficiency as clearly demonstrated by re-exposure. They conclude that given the widespread use of opiates in chronic pain management physicians should raise their level of awareness for adrenal insufficiency and look for it generously.
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