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Dihydrotestosterone stimulates aldosterone secretion by H295R human adrenocortical cells
Molecular and Cellular Endocrinology, 04/17/09
Yanes LL et al. - Supraphysiological concentrations of DHT-stimulated aldosterone secretion by human adrenal cells by the calmodulin/CaMK and protein kinase C intracellular signaling pathways but independently of the classical androgen receptor. Supraphysiological doses of androgen may promote cardiovascular diseases via stimulation of aldosterone secretion.
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