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See Latest ArticlesMaternal serum endostatin at gestational weeks 16-20 is elevated in subsequent pre-eclampsia but not in intrauterine growth retardation
Acta Obstetricia et Gynecologica Scandinavica, 04/14/09
Wathen KA et al. - The results were further confirmed by receiver operating characteristic analysis showing an area under the curve of 0.64 for endostatin to identify subsequent pre-eclampsia, and 0.71 in cases of severe pre-eclampsia. Optimal cut-off values were determined and used for calculations of sensitivity and specificity, which were 80 and 52% in pre-eclampsia, and 80 and 65% in the severe form of the disease. Conclusions. The concentrations of endostatin in maternal serum at 16-20 weeks' of gestation are associated with an increased risk of pre-eclampsia but not IUGR.
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