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Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces mRNA translation initiation and nutrient sensing in fetal liver and skeletal muscle
Endocrinology, 04/22/09
Thorn SR et al. - PI-IUGR is associated with reduced BCAA uptake and growth factors, yet up-regulation of proximal insulin signaling and a marked increase in the gluconeogenic pathway. Lack of activation of several energy and stress sensors in fetal liver and skeletal muscle, despite hypoxia and low energy status, suggests a novel strategy for survival in the PI-IUGR fetus, but with potential maladaptive consequences for reduced nutrient sensing and insulin sensitivity in postnatal life.
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Timing and Trajectories of Fetal Growth Related to Cognitive Development in Childhood
American Journal of Epidemiology, 11/05/09
Embryonic development and pregnancy test sensitivity: the importance of earlier pregnancy detection
Women's Health, 11/03/09
Non-Linear and Gender-Specific Relationships Among Placental Growth Measures and The Fetoplacental Weight Ratio
Placenta, 11/02/09
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